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Do not mix these ingredients with Retinol

Retinol can be tricky and may cause irritation, peeling, or inflammation when paired with certain ingredients.

Learn what not to mix with Retinol in this blog.

In this post, we will cover

  1. Understanding Retinol and its effects
  2. What not to mix with Retinol?
  3. General tips for using Retinol safely
  4. Frequently Asked Questions

Retinol, or Vitamin A1, is one of the most celebrated ingredients in skincare, renowned for its ability to fight acne, reduce fine lines, boost collagen and brighten skin. 

However, despite its effectiveness, Retinol can be tricky to use and may not pair well with certain ingredients, potentially causing irritation, peeling or inflammation.

This guide breaks down ingredients you should never mix with Retinol and the science behind it.

It also offers expert tips on incorporating Retinol into your routine safely and effectively.

Understanding Retinol and its effects

Before diving into what not to mix with Retinol, it is essential to understand what Retinol does and how it interacts with your skin.

What is Retinol?

Retinol, a Vitamin A derivative, is a clinically proven compound known for its ability to accelerate cellular turnover, and stimulate collagen synthesis. 

These properties make it highly effective in managing acne, minimizing signs of aging and enhancing skin texture and tone for a more rejuvenated appearance.

How Retinol Works?

When applied to the skin, Retinol is converted into retinoic acid, which is its active form

This active ingredient works by attaching to special receptors in skin cells, where it helps speed up the process of shedding old, dead skin cells and replacing them with new ones. 

Retinol also boosts fibroblast activity that stimulates the production of elastin, which are proteins that keep the skin firm and reduce wrinkles. 

Ingredients to avoid mixing with Retinol

While Retinol offers numerous skin benefits, it can react poorly with certain ingredients, diminishing its effectiveness or causing irritation. 

Understanding which ingredients don’t pair well with Retinol is crucial to maintaining a balanced skincare routine.

Below are some key ingredients that should be avoided or used cautiously when incorporating Retinol into your regimen - 

1. Exfoliating Acids (AHAs and BHAs)

Alpha-hydroxy acids (AHAs) and beta-hydroxy acids (BHAs) are chemical exfoliants commonly used in skincare products to remove dead skin cells. 

AHAs like Glycolic Acid and Lactic Acid and BHAs like Salicylic Acid, work by breaking down the bonds between dead skin cells, revealing smoother skin underneath.

Why it doesn’t mix well with Retinol

Since Retinol is already an exfoliant, using AHAs or BHAs in conjunction with it can cause excessive exfoliation, leading to irritation, dryness and increased sensitivity. 

When you over-exfoliate your skin, it can disrupt the skin barrier, making your complexion more susceptible to damage from environmental factors like UV rays and pollution.

Tip: If you are using an exfoliating acid, limit it to alternate nights, or use it in the morning while reserving Retinol for your night-time routine. 

This way, you can enjoy the benefits of both ingredients without causing irritation to your skin.

2. Vitamin C

Vitamin C is an antioxidant that helps brighten the skin, protect against free radicals and even out skin tone. It also promotes collagen production, which can aid in skin firming. 

Why it doesn’t mix well with Retinol

Retinol and Vitamin C work at different pH levels. Vitamin C (particularly in its L-ascorbic acid form) is most effective in an acidic environment, while retinol works better in a neutral to slightly acidic pH. 

When used together, they can neutralize each other, diminishing their effectiveness. 

Additionally, both are potent ingredients that can cause irritation when used together, especially for sensitive skin.

Tip: To get the most out of both ingredients, use Vitamin C in the morning and Retinol at night. This allows each ingredient to work at its optimal pH without interfering with the other.

3. Benzoyl Peroxide

Benzoyl peroxide is commonly used in acne treatments for its ability to kill acne-causing bacteria and reduce inflammation. It is highly effective for treating active breakouts.

Why it doesn’t mix well with Retinol

Benzoyl peroxide is a powerful ingredient that can cause drying on the skin. 

When combined with Retinol, both ingredients can intensify dryness, redness and peeling, leading to significant irritation. 

Additionally, Benzoyl Peroxide can break down the retinol molecule, making it less effective.

Tip: Alternatively, use Benzoyl peroxide and retinol on alternate nights to prevent overloading your skin.

4. Physical Exfoliants

Physical exfoliants include face scrubs with granules or tools like cleansing brushes and facial sponges that manually slough off dead skin cells.

Why it doesn’t mix well with Retinol

Retinol already accelerates the skin’s natural exfoliation process, so combining it with physical exfoliants can cause excessive irritation and redness.

The abrasive action of scrubs or brushes can strip away the skin’s protective barrier, increasing overall skin sensitivity.

Tip: Stick to gentle exfoliation and avoid using harsh scrubs at nights when you apply retinol. Opt for a mild cleanser that does not disrupt the skin’s balance.

5. Hydroquinone

Hydroquinone is a skin-lightening agent that helps fade dark spots, hyperpigmentation, and melasma by inhibiting melanin production.

Why it doesn’t mix well with Retinol

Both retinol and hydroquinone are powerful treatments for the skin.

While they work well individually, combining them can be too much for the skin to handle, leading to irritation, redness, and peeling. 

Additionally, both ingredients can increase skin sensitivity, particularly to sunlight.

Tip: Consult a dermatologist if you need both retinol and hydroquinone in your skincare routine.

6. Essential Oils

Essential oils are concentrated plant extracts known for their aromatic properties and potential skin benefits, such as soothing or anti-inflammatory effects.

Why it doesn’t mix well with Retinol

Essential oils can be irritating to the skin, especially when used with a potent ingredient like Retinol. 

Some essential oils, such as tea tree oil or citrus oils, can be photosensitive, which increases the risk of sun damage. 

Others might have a tendency towards allergic reactions or irritation when paired with Retinol.

Tip: If you want to use essential oils in your skincare routine, avoid mixing them with retinol. Always conduct a patch test before applying them to your face.

7. Fragrance-heavy Products

Fragrance-heavy skincare products contain high concentrations of synthetic or natural fragrances, which are added to enhance the scent of the product.

Such fragrances can cause irritation, allergic reactions, or sensitivity, particularly for those with sensitive skin or conditions like eczema or rosacea.

Why it doesn’t mix well with Retinol

Fragrances are known to irritate the skin, particularly when combined with active ingredients like Retinol.

The alcohol or synthetic chemicals in fragranced products can dry out the skin, making it more prone to sensitivity and allergic reactions.

Tip: Opt for fragrance-free non-comodogenic skincare products when using retinol. This helps minimize irritation and ensures your skin remains calm and hydrated.

General Tips for Using Retinol Safely

To maximise the benefits of Retinol while minimizing potential side effects, it is important to follow a few key guidelines. 

These tips focus on ensuring that the skin adapts to retinol gradually, helping you achieve the best results without discomfort or damage. Let us dig in a few essentials -

Start slowly

If you are new to Retinol, start by using it once or twice a week and gradually increase the frequency as your skin gets used to it. This helps reduce the risk of irritation.

Hydrate and moisturise

Retinol can dry out the skin, so it is important to keep your skin hydrated. Use a nourishing moisturiser enriched in Ceramides to prevent dryness and soothe the skin.

Use sunscreen

Retinol increases the skin’s sensitivity to the sun. Always apply broad-spectrum sunscreen with SPF 50 or higher during the day, even if you are indoors.

Frequently Asked Questions

Q.1 What is the difference between Retinol and Retinoid?

Retinol is a type of retinoid, which is a broader category of Vitamin A derivatives. 

Retinoids include stronger prescription options like tretinoin, while retinol is available over the counter and is considered gentler, making it suitable for those with sensitive skin. 

Both work by increasing cell turnover and collagen production but vary in potency and side effects.

Q.2 How do I layer Retinol in my skincare routine?

Retinol should be applied after cleansing and toning, but before moisturising. 

Take a small amount of Retinol on your finger tips and apply it evenly across your face. Follow up with a moisturizer to lock in hydration. 

If using other actives, apply Retinol in the evening, as it increases sensitivity to UV light. Always apply sunscreen the next morning.

Q.3 Should I use retinol if I have sensitive skin?

Retinol can be used on sensitive skin, but it should be introduced cautiously. 

Start with a low concentration (such as 0.1%) and use it 1-2 times a week. Gradually increase use as your skin builds tolerance. 

Pairing Retinol with soothing ingredients like Hyaluronic Acid can help prevent irritation.

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Skin peeling due to Retinol? A complete guide on how to treat it

how to get rid of skin peeling due to retinol

Skin peeling due to Retinol? A complete guide on how to treat it

Why does Retinol cause skin peeling? With age, the dead skin cells accumulate on the topmost layer of your skin, giving it a leathery, wrinkly look. Retinol sheds dead skin cells by speeding up the skin cell turnover cycle, helping you get a Dewey, luminous look. However, there can be a gap between where the dead skin cells are shed and the new ones come to the surface of your skin. During that gap, your skin can become dry, flaky or even start to peel. This is also known as the Retinisation phase, wherein your skin is getting accustomed to Retinol. Other than that, here are a few reasons why Retinol might cause skin peeling - The concentration of Retinol might be too high Let me explain this with an analogy. Let’s say you have just started running—and the first session you try is a marathon. Sounds awful, right? Slow and steady wins the race. The same goes for the Retinol. To take in all the benefits of Retinol, you need to start with a lower concentration, such as 0.1% or 0.3% and then eventually move up to higher ones. Often, individuals who experience severe side effects from retinol have started with a higher concentration from the beginning. READ - What is the right percentage of Retinol for your skin?   Frequency  Even if you are using the right percentage of Retinol for your skin, using it too frequently can be the cause of peeling. The best way to begin with Retinol is to use it 2 - 3 times a week, during your nighttime routine. And once you feel your skin is no stranger to Retinol, you can increase the frequency. I’d say, give it 4 - 6 weeks before you start using Retinol every day. Skincare routine lacks hydrating ingredients By incorporating more hydrating ingredients into your routine, you can prevent the unpleasant side effects of retinol, such as flakiness, peeling, and itchiness. Here are three hydrating ingredients that pair really well with Retinol - Ceramide Hyaluronic Acid Niacinamide We will explore this topic in detail later in the blog. How long does skin peeling from Retinol last? Skin peeling from Retinol is not entrenched—it’s not like it will happen to everyone. In most cases, individuals with dry skin are more likely to deal with skin peeling after using Retinol—as compared to oily skin. Retinol causes the flaking of dead skin cells, leading to dryness and peeling, particularly in the areas of your face that are already prone to dryness. However, these side effects are not perennial—in fact—they will only last a few days (3 to 8 days). Plus, it’s only a one-time deal. What’s important here is to give your skin time to adjust. What are the best ways to treat skin peeling from Retinol? Following solutions can reduce the severity of skin peeling - Apply a moisturiser containing Hyaluronic Acid Hyaluronic Acid is one of the most powerful humectants—it retains and increases skin hydration.  A 2021 study says Hyaluronic Acid increases skin hydration immediately after the application—making skin smooth and plump. Moreover, a 2012 study says Hyaluronic Acid is a key molecule in the ageing process.  The study indicates that a low molecular weight form of Hyaluronic Acid can effectively diminish the appearance of fine lines and wrinkles. Therefore, combining Hyaluronic Acid with Retinol can prevent dryness and peeling while also treating skin ageing more effectively. READ - Retinol VS Hyaluronic Acid Use Retinol and Niacinamide together A 2020 study indicates that the effectiveness of Retinol is enhanced when combined with Niacinamide. According to a 2008 study, Niacinamide provides an extra barrier for your skin, helping to counteract potential irritation caused by retinol. READ - Everything you need to know about using Retinol and Niacinamide together Do not skip your sunscreen Retinol can make your skin sensitive to the sun—increasing the skin's susceptibility to UV damage. So instead of solving your skin problems, Retinol might end up exacerbating them.  Therefore, it is highly recommended to use sunscreen when you are using Retinol (remember, sunscreen is the main character of your skincare routine). Here is what you need in a sunscreen - SPF 50 or above Contains both mineral and chemical sunscreen filters PA ++++ Also, if you are staying in the sun for too long, make sure to reapply sunscreen every 3-4 hours. Avoid irritation If you're experiencing an adverse reaction from Retinol, here are some things you should stop doing right away: Taking hot or cold showers Touching your skin frequently Avoid exfoliating Reduce the frequency of application Don’t use harsh skincare products During the retinization phase, make sure to avoid the following -  Salicylic Acid Glycolic Acid Benzoyl Peroxide Harsh exfoliants and scrubs These skincare ingredients can interact negatively with Retinol, leading to irritation, sensitivity, and peeling—particularly if you're new to Retinol. How to safely use Retinol to avoid skin peeling? While you can't completely avoid the "Retinol uglies," there are ways to minimise them. And guess what?  It all comes down to how you use Retinol.  Here is the best way to use Retinol, according to Dermatologists -  Wash your face with a mild cleanser and wait for at least 30 minutes Avoid applying Retinol immediately after washing your face.  Cleansing strips away your skin's natural protective oils, leaving it more prone to irritation from Retinol. Start with a pea-sized amount  This small quantity is sufficient to cover your entire face and ensure that you're not overusing the product.  Try sandwich method Apply a layer of hydrating moisturiser. Follow with a pea-sized amount of Retinol across your entire face. Finish with another layer of moisturiser. This method is highly recommended to minimise some of the potential adverse effects of Retinol. Additional tips - Start with a low concentration of Retinol, such as 0.1% or 0.3%. Apply Retinol once or twice per week—during the night. Use sunscreen during the day to avoid any sun damage. Avoid applying Retinol near your eyes, nose and lips.

Aayush Maggu 09. 08. 2024

Retinol VS Hyaluronic Acid: Which one is better for treating acne, dark circles, fine lines and wrinkles

Hyaluronic Acid Vs Retinol: Which One Should You Go For?

Retinol VS Hyaluronic Acid: Which one is better for treating acne, dark circles, fine lines and wrinkles

How are Retinol and Hyaluronic Acid different from each other? Retinol is widely regarded as the most effective anti-ageing topical treatment. A 2012 study highlighted Hyaluronic Acid as a key molecule in the ageing process. The study suggests that a low molecular weight variant of Hyaluronic Acid can effectively reduce the appearance of fine lines and wrinkles. Thus, both Retinol and Hyaluronic Acid can be considered effective anti-ageing treatments. But is Hyaluronic Acid as potent as Retinol? Does HA possess the ability to penetrate the deeper layers of the skin and mitigate free radicals like Retinol does? No, HA works quite differently from Retinol. Let's go over the key differences between Retinol and Hyaluronic Acid to help you determine which is better suited for your specific skin concerns. 1. Hyaluronic Acid is primarily a humectant that hydrates and retains water in the skin. Retinol, a Vitamin A derivative, promotes cell renewal and boosts collagen and elastin production. A 2021 study shows that HA can immediately boost skin hydration, making the skin smooth and plump. Whereas, Retinol stimulates collagen and elastin production in the skin, enhancing blood flow. This helps Retinol counteract skin concerns like wrinkles, fine lines, and hyperpigmentation. 2. Hyaluronic Acid mostly works on the surface of your skin, whereas Retinol penetrates deeper into the skin. Hyaluronic Acid comes in 4 variants: raw form, hydrolyzed form, alkaline form, and cross-linked form.  Raw and hydrolyzed forms have high molecular weight and are unable to penetrate deeper layers of your skin. Thus, it stays on the outer layer of your skin and delivers hydration where it's required.  However, alkaline (sodium hyaluronate) and cross-linked forms have low molecular weight and can penetrate the deeper layers of skin. On the other hand, over-the-counter Retinol creams are available in various concentrations, for example, 0.1% to 2%.  Regardless of the concentration, Retinol has low molecules that go deep beneath the epidermis (outer layer of skin) to the dermis.  3. Hyaluronic Acid is suitable for all skin types and can be used daily, while Retinol, typically used at night, requires gradual introduction due to its potency and may initially cause irritation. Hyaluronic Acid is considered to be safe for all skin types, can be used every day, and does not cause any adverse effects. Out of all clinical trials conducted to prove the efficacy of HA—not one highlights any side effects of this ingredient.  Retinol, on the flip side, requires cautious use. If you are new to Retinol, it is suggested to start with low concentration and use it once a week during your nighttime routine. Moreover, to some individuals, especially the ones with acne-prone or sensitive skin, Retinol can cause adverse reactions like purging, irritation, redness and peeling. 4. Results from Retinol can take weeks or months to show, while Hyaluronic Acid increases skin hydration immediately upon application. Retinol has numerous benefits including reducing the appearance of fine lines and wrinkles, hyperpigmentation, and acne scars. But, Retinol takes time to work. It requires consistent usage.  The first few applications may even cause a few adverse effects. However, there is one short-term benefit you can expect. After a few applications, Retinol will exfoliate the dead skin cells and unclog your pores—preventing the formation of acne over time. Retinol vs Hyaluronic Acid: Which one is better for fine lines and wrinkles? If fine lines and wrinkles are among your skin concerns, look no further than Retinol. A 2006 study says that Retinoids, including Retinol, are the most promising agents available for the treatment of ageing and photoaging. Retinol increases collagen production in the skin and stimulates the production of new blood vessels—reducing the appearance of fine lines and wrinkles. Moreover, once the Retinol molecules reach the deeper layer of your skin, they reduce/balance free radicals (A 2010 study found that free radicals damage skin cells, leading to premature ageing). But, to see results, you need to be consistent with Retinol. Experts say it can take up to 6 months before the improvements in wrinkles are apparent. Retinol vs Hyaluronic Acid: Which is more suitable for treating acne?  Retinol is more effective than Hyaluronic Acid when it comes to treating acne. In fact, it is approved for treating acne. A 2021 study says Retinol's anti-inflammatory properties make it highly effective in treating acne and improving hyperpigmentation. Another reason why Retinol is considered a suitable treatment for acne is its ability to unclog pores. Clogged pores, caused by a buildup of dirt, oil, or dead skin cells, are a common skin condition. They are also the most common cause of acne. On the other hand, there are not many studies that prove the effectiveness of HA for the treatment of acne.  The only relevant information available is a 2017 clinical trial that says HA can regulate sebum production, helping to prevent acne over time. Excess sebum production is a major cause of acne. But HA does not target acne directly, thus Retinol is a better option. READ: How Effective is Retinol for Treating Acne? Which one is better for treating dark circles? For treating dark circles or under-eye bags, Hyaluronic Acid is a safer option.  It's gentle enough to use around the eyes, unlike Retinol cream, which is quite potent and should be avoided on sensitive areas such as around the eyes, corners of the nose, and corners of the mouth. HA will hydrate and brighten the skin under the eye—reducing the appearance of dark circles. Can you use Retinol and Hyaluronic Acid together?  Yes, you can use Retinol and Hyaluronic Acid together—this combination will not cause any adverse effects. In fact, these ingredients help each other work better.  A clinical trial conducted to test the efficacy of a cream containing low concentration of Retinol and Hyaluronic Acid, says that the combination significantly reduces the appearance of fine lines and wrinkles. The combination can also be used to address skin concerns like pigmentary spots, uneven skin tone, and dullness.  Can Hyaluronic Acid help you avoid Retinol purge?  While Hyaluronic Acid may help with dryness caused by Retinol, it cannot help with skin purging.  Retinol speeds up the cell renewal process—in which your skin is basically trying to get rid of all the unwanted/dead skin cells. These cells are pushed to the surface of your skin—appearing as tiny, red bumps that can be sensitive and painful when touched.  But don’t worry, this is just a phase, which will last for a few days and then your skin will turn back to normal. Also keep in mind that it does not happen to everyone. During the initial phase of using Retinol—where the purging most likely occurs—you can use a hydrating moisturiser to strengthen your skin barrier. Also make sure not to use any other harsh skincare ingredient. READ: Retinol Purge? 5 Easiest Ways To Ease It References Goulden V. Guidelines for the management of acne vulgaris in adolescents. Paediatr Drugs. 2003;5(5):301-13. doi: 10.2165/00128072-200305050-00003. PMID: 12716217. Lobo, V., Patil, A., Phatak, A., & Chandra, N. (2010). Free radicals, antioxidants and functional foods: Impact on human health. Pharmacognosy Reviews, 4(8), 118-126. Mukherjee, S., Date, A., Patravale, V., Korting, H. C., Roeder, A., & Weindl, G. (2006). Retinoids in the treatment of skin aging: An overview of clinical efficacy and safety. Clinical Interventions in Aging, 1(4), 327-348. Draelos, Z. D., Diaz, I., Namkoong, J., Wu, J., & Boyd, T. (2021). Efficacy Evaluation of a Topical Hyaluronic Acid Serum in Facial Photoaging. Dermatology and Therapy, 11(4), 1385-1394.  Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-Endocrinology, 4(3), 253-258.

Aayush Maggu 05. 07. 2024
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